alienate — If you alienate someone, you make them become unfriendly or unsympathetic towards you.
anger — Anger is the strong emotion that you feel when you think that someone has behaved in an unfair, cruel, or unacceptable way.
antagonize — If you antagonize someone, you make them feel angry or hostile towards you.
contaminate — If something is contaminated by dirt, chemicals, or radiation, they make it dirty or harmful.
embitter — Cause (someone) to feel bitter or resentful.
harm — a U.S. air-to-surface missile designed to detect and destroy radar sites by homing on their emissions.
impair — to make or cause to become worse; diminish in ability, value, excellence, etc.; weaken or damage: to impair one's health; to impair negotiations.
infect — to affect or contaminate (a person, organ, wound, etc.) with disease-producing germs.
injure — to do or cause harm of any kind to; damage; hurt; impair: to injure one's hand.
rankle — (of unpleasant feelings, experiences, etc.) to continue to cause keen irritation or bitter resentment within the mind; fester; be painful.
taint — the area between the testicles or vulva and the anus; the perineum.